Germinoma tumor

Tumors of the germ cells can be categorized into five forms:
  • Germinoma
  • Teratoma
  • Endodermal sinus tumor
  • Embryonal carcinoma and
  • Choriocarcinoma

Cells responsible for the occurrence of germinoma grow in the pineal region, mainly affecting the medial structures of the CNS (Central Nervous System), in the second decade of life, prevalent in males. Germinoma was named this way after discovering the overlapping with the testicular seminomas. Histopathologically, there is a uniform composition of germ cells and cytoplasm rich in glycogen.

Also, lymphocytes are present in the tumor mass. These tumors are immune to placental alkaline phosphates.

Also in the group with germ cell tumors, teratomas are also covered.

Symptoms of intracranial tumors depend on age, tumor location and its nature. Symptoms can be divided into two groups:

– Symptoms of increased intracranial pressure;

– Symptoms of brain lesion, either by tumor or by the associated cerebral edema.

The tendency of tracking it can lead to early and frequent occurrence of obstruction of circulation system. This makes the initial symptoms in the majority of intracranial tumors in children to be more like signs of ICH rather than neurological disorders.

Symptoms of increased intracranial pressure

They have been widely discussed in the ICH syndrome.

 

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The headache may be the only clinical manifestation of the syndrome of ICH, which in fact is often misinterpreted as intestinal parasites, refractive disorders, somatic disorders, migraine, oto-mastoiditis, and sinusitis. The characteristics of headache which are its improvement after vomiting after it had already reached its maximum intensity. Sometimes headache occurs when the patient enters the standing position and can be remitted in other positions or when the patient flexes its head. This type of headache occurs in the posterior cranial fossa tumors. Headache may occur in emergencies, which lasts several minutes.

Vomiting occurs in 70-80% of cases, regardless of the location and type of tumor. Vomiting may be associated with abdominal pain and thus simulate an abdominal condition as appendicitis, etc. As they cause dehydration, vomiting can lead to temporary relief of the syndrome of ICH. Vomiting constitutes the onset of clinical sign of intracranial tumors. Nausea may accompany vomiting, but these are found in 20% of cases.

Papillary edema, as a manifestation of ICH is rarely found at extreme ages.

The mortality rate after 5 years is relatively high, between 70 and 90 percent. The cause of this disorder in not yet known. As in almost all cases of tumors, the treatment options are the same: radiation intake, surgery and chemotherapy.

Tumors of the germ cells can be categorized into five forms:

-germinoma

-Teratoma

-Endodermal sinus tumor

-Embryonal carcinoma and

-Choriocarcinoma

Cells responsible for the occurrence of germinoma grow in the pineal region, mainly affecting the medial structures of the CNS (Central Nervous System), in the second decade of life, prevalent in males. Germinoma was named this way after discovering the overlapping with the testicular seminomas. Histopathologically, there is a uniform composition of germ cells and cytoplasm rich in glycogen. Also, lymphocytes are present in the tumor mass. These tumors are immune to placental alkaline phosphates.
Also in the group with germ cell tumors, teratomas are also covered.
Symptoms of intracranial tumors depend on age, tumor location and its nature.
Symptoms can be divided into two groups:
– Symptoms of increased intracranial pressure;
– Symptoms of brain lesion, either by tumor or by the associated cerebral edema.
The tendency of tracking it can lead to early and frequent occurrence of obstruction of circulation system. This makes the initial symptoms in the majority of intracranial tumors in children to be more like signs of ICH rather than neurological disorders.

Symptoms of increased intracranial pressure
They have been widely discussed in the ICH syndrome
.
The headache may be the only clinical manifestation of the syndrome of ICH, which in fact is often misinterpreted as intestinal parasites, refractive disorders, somatic disorders, migraine, oto-mastoiditis, and sinusitis. The characteristics of headache which are its improvement after vomiting after it had already reached its maximum intensity. Sometimes headache occurs when the patient enters the standing position and can be remitted in other positions or when the patient flexes its head. This type of headache occurs in the posterior cranial fossa tumors. Headache may occur in emergencies, which lasts several minutes.
 Vomiting occurs in 70-80% of cases, regardless of the location and type of tumor. Vomiting may be associated with abdominal pain and thus simulate an abdominal condition as appendicitis, etc. As they cause dehydration, vomiting can lead to temporary relief of the syndrome of ICH.  Vomiting constitutes the onset of clinical sign of intracranial tumors. Nausea may accompany vomiting, but these are found in 20% of cases.
Papillary edema, as a manifestation of ICH is rarely found at extreme ages.

The mortality rate after 5 years is relatively high, between 70 and 90 percent. The cause of this disorder in not yet known. As in almost all cases of tumors, the treatment options are the same: radiation intake, surgery and chemotherapy. 

flu, germinoma, headache, ich, intracranial, symptoms, syndrome, tumor, tumors, vomiting